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嘌呤霉素 Puromycin 10 mg/mL

Certificates of Analysis

Cross Reference Table

Catalog Number:S250J0
Size:1 mL

Product Description

嘌呤霉素(Puromycin)是由白黑链霉菌(Streptomyces alboniger)发酵代谢产生的一种氨基糖苷类抗生素,通过抑制蛋白质合成而杀死革兰氏阳性菌及各种动物和昆虫细胞,某种特殊情况下也有效作用于大肠杆菌。嘌呤霉素作为氨酰-tRNA分子3’末端的类似物,能够与核糖体的A位点结合并掺入到延伸的肽链中。但是嘌呤霉素同A位点结合后,不会参与随后的任何反应,从而导致蛋白质合成的提前终止并释放出C-末端含有嘌呤霉素的不成熟多肽。

对嘌呤霉素的抗性取决于编码嘌呤霉素N-乙酰转移酶(PAC)pac基因,遗传工程研究使用的pac基因分离自嘌呤霉素产生菌Streptomyces alboniger

嘌呤霉素普遍应用于筛选和维持培养含pac基因的哺乳动物稳定转染细胞。嘌呤霉素在细胞稳转株筛选中的普遍应用与慢病毒载体的特性有关,现在商业化的慢病毒载体多数都携带pac基因。在某些特定情况下,嘌呤霉素亦可以用来筛选转化携带pac基因质粒的大肠杆菌菌株。

本产品使用注射用水(Water-For-Injection)配制。

本产品供科学研究使用,用于组织和细胞的体外培养。禁止临床使用。

Quality Assurance

Products from Shanghai BasalMedia Technologies Co.,LTD are all manufactured in cGMP-compliant facilities. Shanghai BasalMedia Technologies Co.,LTD is certified with ISO9001:2015 and ISO13485:2016 quality system standards.

Manufacturing Assurance

We have been committed to adopting modern management models to make all production and operation activities, including safety production management, scientific, standardized and legalized. It comprehensively promotes the occupational health and safety management system in a scientific way to create a healthy, safe and friendly working environment for every employee of BasalMedia Technologies. We have passed the ISO45001:2018 Occupational Health and Safety Management System Certification and ISO14001:2015 Environmental Management System Certification.
Catalog Number Size Price (CNY) Availability
S250J0 1 mL 400.00

Specifications

Application Area 细胞培养相关试剂
Product Category 细胞培养抗生素
Form 液体
Sterility 过滤除菌
Shelf Life 24个月
With/Without Additives(+ [+]10 mg/mL 嘌呤霉素
Endotoxin ≤5 EU/mL
pH Level 6.0~7.0
Storage Conditions -30~-5 ℃,避光
Classification 无动物源
Shipping Conditions 干冰

Documents

Certificates of Analysis

Cross Reference Table

Quality Assurance

Products from Shanghai BasalMedia Technologies Co.,LTD are all manufactured in cGMP-compliant facilities. Shanghai BasalMedia Technologies Co.,LTD is certified with ISO9001:2015 and ISO13485:2016 quality system standards.

Manufacturing Assurance

We have been committed to adopting modern management models to make all production and operation activities, including safety production management, scientific, standardized and legalized. It comprehensively promotes the occupational health and safety management system in a scientific way to create a healthy, safe and friendly working environment for every employee of BasalMedia Technologies. We have passed the ISO45001:2018 Occupational Health and Safety Management System Certification and ISO14001:2015 Environmental Management System Certification.
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Tel:021-37196939

Email:info@basalmedia.com

Address:No.1569, LanFeng Rd, Feng Xian District, Shanghai City, China


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